St. John's and Michigan State trying to buck history: since the field expanded in 1985, forty 1 or 2 seeds were unranked pre-season; none of them made the final four and the majority lost in the first weekend
The Teams and When They Lost:
First Round: 4 (23 Purdue, 18 Virginia, 13 Georgetown, 97 South Carolina)
Second Round: 18 (23 Marquette, 16 Xavier, 14 Villanova, 11 Notre Dame, 06 Tennessee, 06 Ohio State, 04 Mississippi St, 03 Wake Forest, 02 Cincinnati, 99 Miami, 98 Cincinnati, 92 USC, 90 Kansas, 90 Purdue, 87 Temple, 86 St. John's, 85 Michigan, 85 VCU)
Sweet Sixteen: 10 (24 Iowa St, 22 Arizona, 21 Alabama, 13 Miami, 12 Michigan St, 10 Syracuse, 99 Auburn, 94 UConn, 90 Michigan St, 89 Indiana)
Elite Eight: 8 (16 Oregon, 10 Kansas St, 02 UConn, 02 Oregon, 00 Iowa State, 94 Missouri, 90 UConn, 85 North Carolina)