Firefly Lane and Dead to Me

Two shows with great, interesting, highly flawed female leads whose platonic love is almost transcendental. FL is a lot more about sentimental drama and DTM is purely chaotic drama. Great entertainment with so much focus on the friendship between two women. But one thing that irks me is that both have one of the friends die of cancer in the end. Is there a single show about two best friends that doesn't end so tragically?