What are your mutation setups?

I just unlocked my 5th mutation slot in my playthrough, and I'm wondering what you all like to run? I use the 4 elemental weapons (mint mace, coaltana, acid edge and salty mother demon club).

I've been using meat shield, natural explorer, cardio fan, buff lungs for general exploring, but I haven't really dove into the different presets.

What do you guys use and what would you all recommend me to use?