Not sure if I need to make different mod folders for different gameplays

Hey, I’m trying to play like a medieval game in sims and I have a mods folder with all my regular mods in it and I was wondering if I need to make a whole new mods folder so they don’t mix with my regular mods if that makes any sense? I want them to be organized with like my different gameplays but I’m not too sure how to do that.