Kalvin Ter during midnight (winter)

Hi! I'll be visiting Budapest in march. I know there's plenty of time left but I bought my returning flight yesterday. Thing is the flight is scheduled at 6 am. I know that the 100E bus has 3 stops in the city, and the closest one from my hotel is Kalvin Ter.

How safe is that area during midnight, in winter? I'm 24M and will probably carry a big luggage to check