Exome vs Genome sequencing for connective tissue disorders?
Hi,
I'm trying to learn more about genetics, specifically genetic testing as my geneticist is encouraging me to sequence my dnd in hope to identify/rule out any connective tissue diseases known to cause aneurysms. He's quoted me the lab fees of approx. $1055usd for full exome sequencing vs $3724usd for full genome sequencing, however he feels the likelihood of finding any known links to my illness is low. Potentially 10% with exome and 15% with genome.
I'd love to get your opinion on if you think it's worth sequencing the full genome or if it's better to stick with just the exome sequencing and waiting 5-10 years to do full genome sequencing when the prices come down and there are better libraries to identify the genes associated with my disorder?
I really hope this post doesn't go against your rules of giving medical advice, as I don't really know anything about this area of science and would really appreciate some help understanding the field.